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成果報告:J-MICC全体に関する論文

  1. Shiwa Y, Hachiya T, Furukawa R, Ohmomo H, Ono K, Kudo H, Hata J, Hozawa A, Iwasaki M, Matsuda K, Minegishi N, Satoh M, Tanno K, Yamaji T, Wakai K, Hitomi J, Kiyohara Y, Kubo M, Tanaka H, Tsugane S, Yamamoto M, Sobue K, Shimizu A.. Adjustment of Cell-Type Composition Minimizes Systematic Bias in Blood DNA Methylation Profiles Derived by DNA Collection Protocols. .PLoS One. 2016;11:e0147519..
  2. Okada R, Naito M, Hattori Y, Seiki T, Wakai K, Nanri H, Watanabe M, Suzuki S, Kairupan TS, Takashima N, Mikami H, Ohnaka K, Watanabe Y, Katsuura-Kamano S, Kubo M, Hamajima N, Tanaka H; Japan Multi-institutional Collaborative Cohort Study Group.. Matrix metalloproteinase 9 gene polymorphisms are associated with a multiple family history of gastric cancer. .Gastric Cancer. (Pulished online, 2016 Apr 6).
  3. Nishida Y, Hara M, Sakamoto T, Shinchi K, Kawai S, Naito M, Hamajima N, Kadota A, Suzuki S, Ibusuki R, Hirata A, Yamaguchi M, Kuriyama N, Oze I, Mikami H, Kubo M, Tanaka H for the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Group.. Influence of cigarette smoking and inflammatory gene polymorphisms on glycated hemoglobin in the Japanese general population. .Preventive Medicine Reports. 2016;3:288-95..
  4. Yin G, Naito M, Wakai K, Morita E, Kawai S, Hamajima N, Suzuki S, Kita Y, Takezaki T, Tanaka K, Morita M, Uemura H, Ozaki E, Hosono S, Mikami H, Kubo M, Tanaka H, for The Japan Multi-institutional Collaborative Cohort (J-MICC) Study Group.. ALDH2 polymorphism is associated with fasting blood glucose through alcohol consumption in Japanese men. .Nagoya J Med Sci. 2016;78:183-93..
  5. Yamaguchi M, Uemura H, Arisawa K, Katsuura-Kamano S, Hamajima N, Hishida A, Suma S, Oze I, Nakamura K, Takashima N, Suzuki S, Ibusuki R, Mikami H, Ohnaka K, Kuriyama N, Kubo M, Tanaka H, the Japan Multi-institutional Collaborative Cohort (J-MICC) Study Group.. Association between brain-muscle-ARNT-like protein-2 (BMAL2) gene polymorphism and type 2 diabetes mellitus in obese Japanese individuals: A cross-sectional analysis of the Japan Multi-Institutional Collaborative Cohort Study. .Diabetes Res Clin Pract. 2015;110:301-8..
  6. Koyama T, Matsui D, Kuriyama N, Ozaki E, Tanaka K, Oze I, Hamajima N, Wakai K, Okada R, Arisawa K, Mikami H, Shimatani K, Hirata A, Takashima N, Suzuki S, Nagata C, Kubo M, Tanaka H.. Genetic variants of SLC17A1 are associated with cholesterol homeostasis and hyperhomocysteinemia in Japanese men. .Scientific Reports (Published online, 2015 Nov 3).
  7. Uemura H, Katsuura-Kamano S, Yamaguchi M, Arisawa K, Hamajima N, Hishida A, Kawai S, Oze I, Shinchi K, Takashima N, Suzuki S, Nakahata N, Mikami H, Ohnaka K, Kuriyama N, Kubo M, Tanaka H; Japan Multi-institutional Collaborative Cohort (J-MICC) Study Group.. A variant of the CLOCK gene and related haplotypes are associated with the prevalence of type 2 diabetes in the Japanese population. .J Diabetes. (Published online, 2015 Sep 16).
  8. Hosono S, Ito H, Oze I, Higaki Y, Morita E, Takashima N, Suzuki S, Shimatani K, Mikami H, Ohnaka K, Ozaki E, Katsuura-Kamano S, Kubo M, Nagata C, Naito M, Hamajima N, Tanaka H; Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Group.. Polymorphisms in CYP19A1, HSD17B1 and HSD17B2 genes and serum sex hormone level among postmenopausal Japanese women. .Maturitas. 2015;82:394-401..
  9. Sugimoto Y, Wakai K, Nakagawa H, Suma S, Sasakabe T, Sakamoto T, Takashima N, Suzuki S, Ogawa S, Ohnaka K, Kuriyama N, Arisawa K, Mikami H, Kubo M, Hosono S, Hamajima N, Tanaka H; J-MICC Study Group.. Associations between polymorphisms of interleukin-6 and related cytokine genes and serum liver damage markers: a cross-sectional study in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study. .Gene. 2015;557:158-62..
  10. Hishida A, Wakai K, Naito M, Suma S, Sasakabe T, Hamajima N, Hosono S, Horita M, Turin TC, Suzuki S, Kairupan TS, Mikami H, Ohnaka K, Watanabe I, Uemura H, Kubo M, Tanaka H; J-MICC Study Group.. Polymorphisms of genes involved in lipid metabolism and risk of chronic kidney disease in Japanese – cross-sectional data from the J-MICC study. .Lipids Health Dis. 2014;13:162..
  11. Hara M, Nakamura K, Nanri H, Nishida Y, Hishida A, Kawai S, Hamajima N, Kita Y, Suzuki S, Mantjoro EM, Ohnaka K, Uemura H, Matsui D, Oze I, Mikami H, Kubo M, Tanaka H. Associations between hOGG1 Ser326Cys polymorphism and increased body mass index and fasting glucose level in the Japanese general population .J Epidemiol. 2014;24:379-84..
  12. Katsuura-Kamano S, Uemura H, Arisawa K, Yamaguchi M, Hamajima N, Wakai K, Okada R, Suzuki S, Taguchi N, Kita Y, Ohnaka K, Kairupan TS, Matsui D, Oze I, Mikami H, Kubo M, Tanaka H. A polymorphism near MC4R gene (rs17782313) is associated with serum triglyceride levels in the general Japanese population: the J-MICC Study .Endocrine. 2014;47:81-9..
  13. Nakamura A, Niimura H, Kuwabara K, Takezaki T, Morita E, Wakai K, Hamajima N, Nishida Y, Turin TC, Suzuki S, Ohnaka K, Uemura H, Ozaki E, Hosono S, Mikami H, Kubo M, Tanaka H. Gene-Gene Combination Effect and Interactions among ABCA1, APOA1, SR-B1, and CETP Polymorphisms for Serum High-Density Lipoprotein-Cholesterol in the Japanese Population .PLoS One. 2013;8:e82046.
  14. Hishida A, Wakai K, Naito M, Tamura T, Kawai S, Hamajima N, Oze I, Imaizumi T, Turin T, Suzuki S, Kheradmand M, Mikami H, Ohnaka K, Watanabe Y, Arisawa K, Kubo M and Tanaka H. Polymorphisms in PPAR genes (PPARD, PPARG and PPARGC1A) and risk of chronic kidney disease in Japanese – cross-sectional data from the J-MICC Study .PPAR Res. 2013, Article ID 980471.

    →「PPAR遺伝子多型と慢性腎臓病の罹りやすさ」

  15. Hishida A, Takashima N, Turin T, Kawai S, Wakai K, Hamajima N, Hosono S, Nishida Y, Suzuki S, Nakahata N, Mikami H, Ohnaka K, Matsui D, Katsuura-Kamano S, Kubo M, Tanaka H, Kita Y. GCK, GCKR polymorphisms and risk of chronic kidney disease in Japanese: cross-sectional data from the J-MICC Study .J Nephrol. 2014;27:143-9..

    →「日本人の慢性腎臓病の罹りやすさは、糖質の代謝に関わるある遺伝子と、タバコとの複合的作用によって決まる可能性がある」

  16. Hishida A, Okada R, Naito M, Morita E, Wakai K, Hamajima N, Hosono S, Nanri H, Turin TC, Suzuki S, Kuwabara K, Mikami H, Budhathoki S, Watanabe I, Arisawa K, Kubo M, Tanaka H. Polymorphism in genes encoding antioxidant enzymes (SOD2, CAT, GPx, TXNRD, SEPP1, SEP15 and SELS) and risk of chronic kidney disease in Japanese – cross-sectional data from the J-MICC study .J Clin Biochem Nutr. 2013;53:15-20.

    →「日本人の慢性腎臓病の発症に関連する遺伝体質の1つが新たに判明した」

  17. Hishida A, Okada R, Yin G, Naito M, Wakai K, Hosono S, Nakamura K, Turin TC, Suzuki S, Niimura H, Mikami H, Otonari J, Kuriyama N, Katsuura S, Kubo M, Tanaka H, Hamajima N. MTHFR, MTR, MTRR polymorphisms and risk of chronic kidney disease in Japanese: cross-sectional data from the J-MICC study .Int Urol Nephrol. 2013;45:1613-20..

    →「葉酸の代謝に関わる遺伝子の違いは、慢性腎臓病の発症に関連する可能性が」

  18. Hishida A, Wakai K, OkadaR, Morita E, Hamajima N, Hosono S, Higaki Y, Turin TC, Suzuki S, Motahareh K, Mikami H, Tashiro N, Watanabe I, Katsuura S, Kubo M, Tanaka H, Naito M. Significant interaction between RETN -420 G/G genotype and lower BMI on decreased risk of Type2 DM in Japanese – the J-MICC Study .Endocr J. 2013;60:237-43.

    →「肥満の糖尿病発症に及ぼす影響の強さは、ある遺伝的体質によって異なる」

  19. Wakai K, Matsuo K, Matsuda F, Yamada R, Takahashi M, Kawaguchi T, Yatabe Y, Ito H, Hosono S, Tajima K, Naito M, Morita E, Yin G, Sakamoto T, Takashima N, Suzuki S, Nakahata N, Mikami H, Ohnaka K, Watanabe Y, Arisawa K, Kubo M, Hamajima N, Tanaka H for the J-MICC Study Group. Genome-wide association study of the genetic factors related to confectionery intake: potential roles of the ADIPOQ gene .Obesity. 2013;21:2413-9..
  20. Higashibata T, Hamajima N, Naito M, Kawai S, Guang Y, Suzuki S, Kita Y, Niimura H, Imaizumi T, Ohnaka K, Arisawa K, Shigeta M, Ito H, Mikami H, Kubo M, Tanaka H, Wakai K. eNOS genotype modifies the effect of leisure-time physical activity on serum triglyceride levels in a Japanese population .Lipids Health Dis. 2012;11:150.
  21. Okada R, Kawai S, Naito M, Hishida A, Hamajima N, Shinchi K, Turin TC, Suzuki S, Mantjoro EM, Toyomura K, Arisawa K, Kuriyama N, Hosono S, Mikami H, Kubo M, Tanaka H, Wakai K, The Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Group. Matrix Metalloproteinase-9 Gene Polymorphisms and Chronic Kidney Disease .Am J Nephrol. 2012;36:444-450.

    →「腎機能が悪くなりやすい遺伝子の型~その2」

  22. Hara M, Higaki Y, Taguchi N, Shinchi K, Morita E, Naito M, Hamajima N, Takashima N, Suzuki S, Nakamura A, Ohnaka K, Uemura H, Nishida H, Hosono S, Mikami H, Kubo M, Tanaka H. Effect of the PPARG2 Pro12Ala Polymorphism and Clinical Risk Factors for Diabetes Mellitus on HbA1c in the Japanese General Population .J Epidemiol. 2012;22:523-31.

    →「HbA1c値への糖尿病危険因子の影響は、遺伝多型で変わる」

  23. Hishida A, Morita E, Naito M, Okada R, Wakai K, Matsuo K, Nakamura K, Takashima N, Suzuki S, Takezaki T, Mikami H, Ohnaka K, Watanabe Y, Uemura H, Kubo M, Tanaka H, Hamajima N. Associations of apolipoprotein A5 (APOA5), glucokinase (GCK) and glucokinase regulatory protein (GCKR) polymorphisms and lifestyle factors with the risk of dyslipidemia and dysglycemia in Japanese – a cross-sectional data from the J-MICC Study .Endocr J. 2012;59:589-99.
  24. Nishiyama T, Kishino H, Suzuki S, Ando R, Niimura H, Uemura H, Horita M, Ohnaka K, Kuriyama N, Mikami H, Takashima N, Mastuo K, Guang Y, Wakai K, Hamajima N, Tanaka H; J-MICC Study Group. Detailed analysis of Japanese population substructure with a focus on the southwest islands of Japan .PLoS One. 2012;7:e35000.

    →「現代日本人はどうやって生じたか」

  25. Hiyoshi M, Uemura H, Arisawa K, Nakamoto M, Hishida A, Okada R, Matsuo K, Kita Y, Niimura H, Kuriyama N, Nanri H, Ohnaka K, Suzuki S, Mikami H, Kubo M, Tanaka H, Hamajima N; J-MICC Study Group. Association between the catechol-O-methyltransferase (rs4680: Val158Met) polymorphism and serum alanine aminotransferase activity .Gene. 2012;496:97-102.

    →「肝機能に関わる遺伝子多型」

  26. Okada R, Wakai K, Naito M, Morita E, Kawai S, Hamajima N, Hara M, Takashima N, Suzuki S, Takezaki T, Ohnaka K, Arisawa K, Hirohata H, Matsuo K, Mikami H, Kubo M, Tanaka H. Pro/anti-inflammatory cytokine gene polymorphisms and chronic kidney disease: a cross-sectional study .BMC Nephrol. 2012;13:2.

    →「腎機能が悪くなりやすい遺伝子の型」

  27. Uemura H, Hiyoshia M, Arisawa K, Yamaguchi M, Naito M, Kawai S, Hamajima N, Matsuo K, Taguchi N, Takashima N, Suzuki S, Hirasada K, Mikami H, Ohnaka K, Yoshikawa A, Kubo M, Tanaka H. Gene variants in PPARD and PPARGC1A are associated with timing of natural menopause in the general Japanese population .Maturitas 2012;71:369-375.

    →「閉経年齢に関わる遺伝子多型」

  28. Wakai K, Hamajima N, Okada R, Naito M, Morita E, Hishida A, Kawai S, Nishio K, Yin G, Asai Y, Matsuo K, Hosono S, Ito H, Watanabe M, Kawase T, Suzuki T, Tajima K, Tanaka K, Higaki Y, Hara M, Imaizumi T, Taguchi N, Nakamura K, Nanri H, Sakamoto T, Horita M, Shinchi K, Kita Y, Turin TC, Rumana N, Matsui K, Miura K, Ueshima H, Takashima N, Nakamura Y, Suzuki S, Ando R, Hosono A, Imaeda N, Shibata K, Goto C, Hattori N, Fukatsu M, Yamada T, Tokudome S, Takezaki T, Niimura H, Hirasada K, Nakamura A, Tatebo M, Ogawa S, Tsunematsu N, Chiba S, Mikami H, Kono S, Ohnaka K, Takayanagi R, Watanabe Y, Ozaki E, Shigeta M, Kuriyama N, Yoshikawa A, Matsui D, Watanabe I, Inoue K, Ozasa K, Mitani S, Arisawa K, Uemura H, Hiyoshi M, Takami H, Yamaguchi M, Nakamoto M, Takeda H, Kubo M, and Tanaka H for the J-MICC Study Group. Profile of Participants and Genotype Distributions of 108 Polymorphisms in a Cross-Sectional Study of Associations of Genotypes With Lifestyle and Clinical Factors: A Project in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study .J Epidemiol. 2011;21:223-35..

    →「お酒への強さに関係する遺伝子にも地域差」

  29. Naito M, Eguchi H, Okada R, Ishida Y, Nishio K, Hishida A, Wakai K, Tamakoshi A, Hamajima N, for the J-MICC Study Group. Controls for monitoring the deterioration of stored blood samples in the Japan Multi-institutional Collaborative Cohort Study (J-MICC Study) .Nagoya J Med Sci. 2008;70:107-115.
  30. The J-MICC Study Group. The Japan Multi-institutional Collaborative Cohort Study (J-MICC Study) to detect gene-environment interactions for cancer .Asian Pac J Cancer Prev. 2007;8:317-323.

    →「ジェイミック研究の概要」

  31. Wakai K, Matsuo K, Matsuda F, Yamada R, Takahashi M, Kawaguchi T, Yatabe Y, Ito H, Hosono S, Tajima K, Naito M, Morita E, Yin G, Sakamoto T, Takashima N, Suzuki S, Nakahata N, Mikami H, Ohnaka K, Watanabe Y, Arisawa K, Kubo M, Hamajima N, Tanaka H for the J-MICC Study Group. Genome-wide association study of the genetic factors related to confectionery intake: potential roles of the ADIPOQ gene .Obesity. 2013;21:2413-9.
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