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成果報告:各研究グループの論文掲載

  1. Sakiyama M, Matsuo H, Nakaoka H, Yamamoto K, Nakayama a, Nakamura T, Kawai S, Okada R, Ooyama H, Shimizu T, Shinomiya N.. Identification of rs671, a common variant of ALDH2, as a gout susceptibility locus. .Scientific Reports. (In Press).
  2. Hattori Y, Naito M, Satoh M, Nakatochi M, Naito H, Kato M, Takagi S, Matsunaga T, Seiki T, Sasakabe T, Suma S, Kawai S, Okada R, Hishida A, Hamajima N, Wakai K.. Metallothionein MT2A A-5G polymorphism as a risk factor for chronic kidney disease and diabetes: Cross-sectional and cohort studies. .Toxicol Sci. (Published online, 2016 Apr 27).
  3. Sakiyama M, Matsuo H, Shimizu S, Nakashima H, Nakamura T, Nakayama A, Higashino T, Naito M, Suma S, Hishida A, Satoh T, Sakurai Y, Takada T, Ichida K, Ooyama H, Shimizu T, Shinomiya N.. The effects of URAT1/SLC22A12 nonfunctional variants, R90H and W258X, on serum uric acid levels and gout/hyperuricemia progression. .Scientific Reports. 2016;6:20148..
  4. Tamura T, Morita E, Kawai S, Sasakabe T, Sugimoto Y, Fukuda N, Suma S, Nakagawa H, Okada R, Hishida A, Naito M, Hamajima N, Wakai K.. No association between Helicobacter pylori infection and diabetes mellitus among a general Japanese population: a cross-sectional study. .SpringerPlus. 2015;4:602..
  5. Nanri H, Hara M, Nishida Y, Shimanoe C, Nakamura K, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Kokaze A, Tanaka K.. Dietary patterns and serum gamma-glutamyl transferase in Japanese men and women. .J Epidemiol. 2015;25:378-86..
  6. Suma S, Naito M, Wakai K, Sasakabe T, Hattori Y, Okada R, Kawai S, Hishida A, Morita E, Nakagawa H, Tamura T, Hamajima N.. Effects of IL6 C-634G polymorphism on tooth loss and their interaction with smoking habits. .Oral Diseases 2015;21,807-13.
  7. Kawai S, Naito M, Morita E, Okada R, Hishida A, Wakai K, Hamajima N.. GGT1 intronic A>G polymorphism affects serum concentration of γ-glutamyltransferase among Japanese healthy adult. .Ningen Dock International 2015;2:65-9..
  8. Shimanoe C, Hara M, Nishida Y, Nanri H, Otsuka Y, Nakamura K, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Tanaka K.. Perceived stress and coping strategies in relation to body mass index: cross-sectional study of 12,045 Japanese men and women. .PLoS One. 2015 Feb 12;10:e0118105..
  9. 森祥子, 徳永嶺, 玉腰浩司, 森田えみ, 内藤真理子, 若井建志, 近藤高明, 岡村雪子, 星野純子, 清水律子, 榊原久孝, 堀容子.. 日本多施設共同コホート研究に参加した家族介護者における運動習慣とストレスの関連. .日本医療看護学会雑誌16巻2号.
  10. Shimizu M, Furusyo N, Mitsumoto F, Takayama K, Ura K, Hiramine S, Ikezaki H, Ihara T, Mukae H, Ogawa E, Toyoda K, Kainuma M, Murata M, Hayashi J.. Subclinical carotid atherosclerosis and triglycerides predict the incidence of chronic kidney disease in the Japanese general population: Results from the Kyushu and Okinawa Population Study (KOPS). .Atherosclerosis. 2014;238:207-212..
  11. Arisawa K, Uemura H, Yamaguchi M, Nakamoto M, Hiyoshi M, Sawachika F, Katsuura-Kamano S.. Associations of dietary patterns with metabolic syndrome and insulin resistance: a cross-sectional study in a Japanese population. .Journal of Medical Investigation. 2014;61:333-44..
  12. Uemura H, Katsuura-Kamano S, Yamaguchi M, Arisawa K.. Relationships of elevated levels of serum hepatic enzymes and alcohol intake with arterial stiffness in men. .Atherosclerosis. 2015;238:83-88..
  13. Nakamoto M, Uemura H, Sakai T, Katsuura-Kamano S, Yamaguchi M, Hiyoshi M, Arisawa K.. Inverse association between soy food consumption and insulin resistance in Japanese adults. .Public Health Nutrition. 2015;18:2031-2040..
  14. Hara M, Shimanoe C, Otsuka Y, Nishida Y, Nanri H, Horita M, Yasukata J, Miyoshi N, Yamada Y, Higaki Y, Tanaka K.. Factors associated with non-participation in a face-to-face second survey conducted 5 years after the baseline survey. .J Epidemiol. 2015;25:117-25..
  15. Uemura H, Katsuura-Kamano S, Yamaguchi M, Nakamoto M, Hiyoshi M, Arisawa K. A family history of stroke is potentially associated with arterial stiffness in Japanese population .Archives of Cardiovascular Diseases. 2014;107:654-63..
  16. Uemura H, Katsuura-Kamano S, Yamaguchi M, Nakamoto M, Hiyoshi M, Arisawa K. Relationship between dietary calcium and arterial stiffness according to dietary vitamin D consumption in men .British Journal of Nutrition. 2014;112:1333-40..
  17. Takada Y, Matsuo H, Nakayama A, Sakiyama M, Hishida A, Okada R, Sakurai Y, Shimizu T, Ichida K, Shinomiya N. Common Variant of PDZK1, Adaptor Protein Gene of Urate Transporters, Is Not Associated with Gout .The Journal of Rheumatology. 2014;41:2330-1..
  18. Suma S, Naito M, Okada R, Kawai S, Yin G, Morita E, Wakai K, Matsuo H, Hamajima N. Associations between body mass index and serum uric acid levels in a Japanese population were significantly modified by LRP2 rs2544390 .Nagoya J Med Sci. 2014;76:333-9..
  19. Sakiyama M, Matsuo H, Chiba T, Nakayama A, Nakamura T, Shimizu S, Morita E, Fukuda N, Nakashima H, Sakurai Y, Ichida K, Shimizu T, Shinomiya N. Common Variants of cGKII/PRKG2 Are Not Associated with Gout Susceptibility .J Rheumatol. 2014;41:1395-7.
  20. Sakiyama M, Matsuo H, Takada Y, Nakamura T, Nakayama A, Takada T, Kitajiri S, Wakai K, Suzuki H, Shinomiya N. Ethnic Differences in ATP-binding Cassette Transporter, Sub-Family G, Member 2 (ABCG2/BCRP): Genotype Combinations and Estimated Functions .Drug Metab Pharmacokinet. 2014;29:490-2..
  21. Nakayama A, Matsuo H, Nakaoka H, Nakamura T, Nakashima H, Takada Y, Oikawa Y, Takada T, Sakiyama M, Shimizu S, Kawamura Y, Chiba T, Abe J, Wakai K, Kawai S, Okada R, Tamura T, Shichijo Y, Akashi A, Suzuki H, Hosoya T, Sakurai Y, Ichida K, Shinomiya N. Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors .Scientific Reports. 2014;4:5227..
  22. Nishida Y, Higaki Y, Taguchi N, Hara M, Nakamura K, Nanri H, Imaizumi T, Sakamoto T, Horita M, Shinchi K, Tanaka K. Objectively measured physical activity and inflammatory cytokine levels in middle-aged Japanese people .Prev Med. 2014;64:81-87.
  23. Oze I, Matsuo K, Kawakita D, Hosono S, Ito H, Watanabe M, Hatooka S, Hasegawa Y, Shinoda M, Tajima K, Tanaka H. Coffee and green tea consumption is associated with upper aerodigestive tract cancer in Japan .Int J Cancer. 2014;135(2):391-400.
  24. Chiba T, Matsuo H, Nagamori S, Nakayama A, Kawamura Y, Shimizu S, Sakiyama M, Hosoyamada M, Kawai S, Okada R, Hamajima N, Kanai Y and Shinomiya N. Identification of a hypouricemia patient with SLC2A9 R380W,a pathogenic mutation for renal hypouricemia type2 .Nucleosides Nucleotides Nucleic Acids. 2014;33:261-5.
  25. Matsuo H, Nakayama A, Sakiyama M, Chiba T, Shimizu S, Kawamura Y, Nakashima H, Nakamura T, Takada Y, Oikawa Y, Takada T, Nakaoka H, Abe J, Inoue H, Wakai K, Kawai S, Guang Y, Nakagawa H, Ito T, Niwa K, Yamamoto K, Sakurai Y, Suzuki H, Hosoya T, Ichida K, Shimizu T, Shinomiya N. ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload .Scientific Reports. 2014;4:3755.
  26. Nakayama A, Matsuo H, Shimizu T, Takada Y, Nakamura T, Shimizu S, Chiba T, Sakiyama M, Naito M, Morita E, Ichida K, Shinomiya N. Common variants of a urate-associated gene LRP2 are not associated with gout susceptibility .Rheumatol Int. 2014 Apr;34(4):473-6.
  27. Sakiyama M, Matsuo H, Shimizu S, Chiba T, Nakayama A, Takada Y, Nakamura T, Takada T, Morita E, Naito M, Wakai K, Inoue H, Tatsukawa S, Sato J, Shimono K, Makino T, Satoh T, Suzuki H, Kanai Y, Hamajima N, Sakurai Y, Ichida K, Shimizu T, Shinomiya N. A common variant of leucine-rich repeat containing 16A (LRRC16A) gene is associated with gout susceptibility .Human Cell. 2014;27:1-4.
  28. Li J, Lindström LS, Foo JN, Rafiq S, Schmidt MK, Pharoah PD, Michailidou K, Dennis J, Bolla MK, Wang Q, Van 't Veer LJ, Cornelissen S, Rutgers E, Southey MC, Apicella C, Dite GS, Hopper JL, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Blomqvist C, Muranen TA, Aittomäki K, Lindblom A, Margolin S, Mannermaa A, Kosma VM, Hartikainen JM, Kataja V, Chenevix-Trench G, Investigators k, Phillips KA, McLachlan SA, Lambrechts D, Thienpont B, Smeets A, Wildiers H, Chang-Claude J, Flesch-Janys D, Seibold P, Rudolph A, Giles GG, Baglietto L, Severi G, Haiman CA, Henderson BE, Schumacher F, Le Marchand L, Kristensen V, Alnæs GI, Borresen-Dale AL, Nord S, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Andrulis IL, Knight JA, Glendon G, Tchatchou S, Devilee P, Tollenaar R, Seynaeve C, Hooning M, Kriege M, Hollestelle A, van den Ouweland A, Li Y, Hamann U, Torres D, Ulmer HU, Rüdiger T, Shen CY, Hsiung CN, Wu PE, Chen ST, Teo SH, Taib NA, Har Yip C, Fuang Ho G, Matsuo K, Ito H, Iwata H, Tajima K, Kang D, Choi JY, Park SK, Yoo KY, Maishman T, Tapper WJ, Dunning A, Shah M, Luben R, Brown J, Khor CC, Eccles DM, Nevanlinna H, Easton D, Humphreys K, Liu J, Hall P, Czene K. 2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy .Nat Commun. 2014;5:4051.
  29. Hedditch EL, Gao B, Russell AJ, Lu Y, Emmanuel C, Beesley J, Johnatty SE, Chen X, Harnett P, George J; Australian Ovarian Cancer Study Group, Williams RT, Flemming C, Lambrechts D, Despierre E, Lambrechts S, Vergote I, Karlan B, Lester J, Orsulic S, Walsh C, Fasching P, Beckmann MW, Ekici AB, Hein A, Matsuo K, Hosono S, Nakanishi T, Yatabe Y, Pejovic T, Bean Y, Heitz F, Harter P, du Bois A, Schwaab I, Hogdall E, Kjaer SK, Jensen A, Hogdall C, Lundvall L, Engelholm SA, Brown B, Flanagan J, Metcalf MD, Siddiqui N, Sellers T, Fridley B, Cunningham J, Schildkraut J, Iversen E, Weber RP, Berchuck A, Goode E, Bowtell DD, Chenevix-Trench G, deFazio A, Norris MD, MacGregor S, Haber M, Henderson MJ. ABCA Transporter Gene Expression and Poor Outcome in Epithelial Ovarian Cancer .J Natl Cancer Inst. 2014;106(7). pii: dju149.
  30. Chen P, Takeuchi F, Lee JY, Li H, Wu JY, Liang J, Long J, Tabara Y, Goodarzi MO, Pereira MA, Kim YJ, Go MJ, Stram DO, Vithana E, Khor CC, Liu J, Liao J, Ye X, Wang Y, Lu L, Young TL, Lee J, Thai AC, Cheng CY, van Dam RM, Friedlander Y, Heng CK, Koh WP, Chen CH, Chang LC, Pan WH, Qi Q, Isono M, Zheng W, Cai Q, Gao Y, Yamamoto K, Ohnaka K, Takayanagi R, Kita Y, Ueshima H, Hsiung CA, Cui J, Sheu WH, Rotter JI, Chen YD, Hsu C, Okada Y, Kubo M, Takahashi A, Tanaka T, van Rooij FJ, Ganesh SK, Huang J, Huang T, Yuan J, Hwang JY, Gross MD, Assimes TL, Miki T, Shu XO, Qi L, Chen YT, Lin X, Aung T, Wong TY, Teo YY, Kim BJ, Kato N, Tai ES. Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians .Diabetes. 2014;63:2551-2562.
  31. DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium; Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium; South Asian Type 2 Diabetes (SAT2D) Consortium; Mexican American Type 2 Diabetes (MAT2D) Consortium; Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES) Consortium, Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, Saleheen D, Wang X, Zeggini E, Abecasis GR, Adair LS, Almgren P, Atalay M, Aung T, Baldassarre D, Balkau B, Bao Y, Barnett AH, Barroso I, Basit A, Been LF, Beilby J, Bell GI, Benediktsson R, Bergman RN, Boehm BO, Boerwinkle E, Bonnycastle LL, Burtt N, Cai Q, Campbell H, Carey J, Cauchi S, Caulfield M, Chan JC, Chang LC, Chang TJ, Chang YC, Charpentier G, Chen CH, Chen H, Chen YT, Chia KS, Chidambaram M, Chines PS, Cho NH, Cho YM, Chuang LM, Collins FS, Cornelis MC, Couper DJ, Crenshaw AT, van Dam RM, Danesh J, Das D, de Faire U, Dedoussis G, Deloukas P, Dimas AS, Dina C, Doney AS, Donnelly PJ, Dorkhan M, van Duijn C, Dupuis J, Edkins S, Elliott P, Emilsson V, Erbel R, Eriksson JG, Escobedo J, Esko T, Eury E, Florez JC, Fontanillas P, Forouhi NG, Forsen T, Fox C, Fraser RM, Frayling TM, Froguel P, Frossard P, Gao Y, Gertow K, Gieger C, Gigante B, Grallert H, Grant GB, Grrop LC, Groves CJ, Grundberg E, Guiducci C, Hamsten A, Han BG, Hara K, Hassanali N, Hattersley AT, Hayward C, Hedman AK, Herder C, Hofman A, Holmen OL, Hovingh K, Hreidarsson AB, Hu C, Hu FB, Hui J, Humphries SE, Hunt SE, Hunter DJ, Hveem K, Hydrie ZI, Ikegami H, Illig T, Ingelsson E, Islam M, Isomaa B, Jackson AU, Jafar T, James A, Jia W, Jockel KH, Jonsson A, Jowett JB, Kadowaki T, Kang HM, Kanoni S, Kao WH, Kathiresan S, Kato N, Katulanda P, Keinanen-Kiukaanniemi KM, Kelly AM, Khan H, Khaw KT, Khor CC, Kim HL, Kim S, Kim YJ, Kinnunen L, Klopp N, Kong A, Korpi-Hyovalti E, Kowlessur S, Kraft P, Kravic J, Kristensen MM, Krithika S, Kumar A, Kumate J, Kuusisto J, Kwak SH, Laakso M, Lagou V, Lakka TA, Langenberg C, Langford C, Lawrence R, Leander K, Lee JM, Lee NR, Li M, Li X, Li Y, Liang J, Liju S, Lim WY, Lind L, Lindgren CM, Lindholm E, Liu CT, Liu JJ, Lobbens S, Long J, Loos RJ, Lu W, Luan J, Lyssenko V, Ma RC, Maeda S, Magi R, Mannisto S, Matthews DR, Meigs JB, Melander O, Metspalu A, Meyer J, Mirza G, Mihailov E, Moebus S, Mohan V, Mohlke KL, Morris AD, Muhleisen TW, Muller-Nurasyid M, Musk B, Nakamura J, Nakashima E, Navarro P, Ng PK, Nica AC, Nilsson PM, Njolstad I, Nothen MM, Ohnaka K, Ong TH, Owen KR, Palmer CN, Pankow JS, Park KS, Parkin M, Pechlivanis S, Pedersen NL, Peltonen L, Perry JR, Peters A, Pinidiyapathirage JM, Platou CG, Potter S, Price JF, Qi L, Radha V, Rallidis L, Rasheed A, Rathman W, Rauramaa R, Raychaudhuri S, Rayner NW, Rees SD, Rehnberg E, Ripatti S, Robertson N, Roden M, Rossin EJ, Rudan I, Rybin D, Saaristo TE, Salomaa V, Saltevo J, Samuel M, Sanghera DK, Saramies J, Scott J, Scott LJ, Scott RA, Segre AV, Sehmi J, Sennblad B, Shah N, Shah S, Shera AS, Shu XO, Shuldiner AR, Sigurðsson G, Sijbrands E, Silveira A, Sim X, Sivapalaratnam S, Small KS, So WY, Stančáková A, Stefansson K, Steinbach G, Steinthorsdottir V, Stirrups K, Strawbridge RJ, Stringham HM, Sun Q, Suo C, Syvanen AC, Takayanagi R, Takeuchi F, Tay WT, Teslovich TM, Thorand B, Thorleifsson G, Thorsteinsdottir U, Tikkanen E, Trakalo J, Tremoli E, Trip MD, Tsai FJ, Tuomi T, Tuomilehto J, Uitterlinden AG, Valladares-Salgado A, Vedantam S, Veglia F, Voight BF, Wang C, Wareham NJ, Wennauer R, Wickremasinghe AR, Wilsgaard T, Wilson JF, Wiltshire S, Winckler W, Wong TY, Wood AR, Wu JY, Wu Y, Yamamoto K, Yamauchi T, Yang M, Yengo L, Yokota M, Young R, Zabaneh D, Zhang F, Zhang R, Zheng W, Zimmet PZ, Altshuler D, Bowden DW, Cho YS, Cox NJ, Cruz M, Hanis CL, Kooner J, Lee JY, Seielstad M, Teo YY, Boehnke M, Parra EJ, Chambers JC, Tai ES, McCarthy MI, Morris AP. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility .Nat Genet. 2014;46:234-44.
  32. Sakiyama M, Matsuo H, Shimizu S, Nakashima H, Nakayama A, Chiba T, Naito M, Takada T, Suzuki H, Hamajima N, Ichida K, Shimizu T, Shinomiya N. A Common Variant of Organic Anion Transporter 4 (OAT4/SLC22A11) Gene Is Associated with Renal Underexcretion Type Gout .Drug Metab Pharmacokinet. (In Press).
  33. Shimanoe C, Otsuka Y, Hara M, Nanri H, Nishida Y, Nakamura K, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Tanaka K. Gender-Specific Associations of Perceived Stress and Coping Strategies with C-Reactive Protein in Middle-Aged and Older Men and Women .Int J Behav Med. (Published Online, October 2, 2013).
  34. Uemura H, Katsuura-Kamano S, Yamaguchi M, Nakamoto M, Hiyoshi M, Arisawa K. Consumption of coffee, not green tea, is inversely associated with arterial stiffness in Japanese men .Eur J Clin Nutr. 2013;67:1109-14.
  35. Kheradmand M, Niimura H, Kuwabara K, Nakahata N, Nakamura A, Ogawa S, Mantjoro EM, Shimatani K, Nerome Y, Owaki T, Kusano K, Takezaki T. Association of Inflammatory Gene Polymorphisms and Conventional Risk Factors With Arterial Stiffness by Age .J Epidemiol. 2013;23:457-65.
  36. Nakayama A, Matsuo H, Shimizu T, Ogata H, Takada Y, Nakashima H, Nakamura T, Shimizu S, Chiba T, Sakiyama M, Ushiyama C, Takada T, Inoue K, Kawai S, Hishida A, Wakai K, Hamajima N, Ichida K, Sakurai Y, Kato Y, Shimizu T, Shinomiya N. A common missense variant of monocarboxylate transporter 9 (MCT9/SLC16A9) gene is associated with renal overload gout, but not with all gout susceptibility .Hum Cell. (Published online, 2013 Aug 29).
  37. Uemura H, Katsuura-Kamano S, Yamaguchi M, Nakamoto M, Hiyoshi M, Arisawa K. Abundant daily non-sedentary activity is associated with reduced prevalence of metabolic syndrome and insulin resistance .J Endocrinol Invest. 2013;36:1069-75.
  38. Matsuo H, Ichida K, Takada T, Nakayama A, Nakashima H, Nakamura T, Kawamura Y, Takada Y, Yamamoto K, Inoue H, Oikawa Y, Naito M, Hishida A, Wakai K, Okada C, Shimizu S, Sakiyama M, Chiba T, Ogata H, Niwa K, Hosoyamada M, Mori A, Hamajima N, Suzuki H, Kanai Y, Sakurai Y, Hosoya T, Shimizu T, Shinomiya N. Common dysfunctional variants in ABCG2 are a major cause of early-onset gout .Scientific Reports. 2013;3:2014.
  39. Matsuo K, Oze I, Hosono S, Ito H, Watanabe M, Ishioka K, Ito S, Tajika M, Yatabe Y, Niwa Y, Yamao K, Nakamura S, Tajima K, Tanaka H. The aldehyde dehydrogenase 2 (ALDH2) Glu504Lys polymorphism interacts with alcohol drinking in the risk of stomach cancer .Carcinogenesis. 2013;34(7):1510-5.
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  48. Garcia_closas M, Cough F, Lindstrom S, Michailidou K, Schmidt MK, Brook M, Orr N, Thie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Mrion P, Fasching PA, Bruch H, Chang-Claude J, Carpenter J, Godwin A, Nevanlinna H, Giles GG, Cox A, Hopper JL, Humphreys MK, Wang Q, Dennis J, Dicks E, Howat WJ, Schoof N, Bojesen SE, Lambrechts D, Broeks A, Andrulis IL, Guenel P, Burwinkel B, Sawyer EJ, Hollestelle A, Fletcher O, Winqvist R, Brenner H, Mannermaa A, Hamann U, Meindl A, Lindblom A, Zheng W, Devillee P, Goldberg MS, Lubinski J, Kristensene V, Swerdlow A, Anton-Culver H, Dork T, Muir K, Matsuo K, Wu AH, Radice P, Teo SH, Shu XO, Blot W, Kang D, Hartman M, Sangrajrang S, Shen CY, Sothey MC, Park DJ, Hammet F, Stone J, Veer LJV, Rutgers EJ, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Peto J, Schrauder MG, Ekici AB, Beckmann MW, dos Santos Silva I, Johnson N, Warren H, Tomlinson I, Kerin MJ, Miller N, Marme F, Schneeweiss A, Sohn C, Truong T, Laurent-Puig P, Kerbrat P, Nordestgaard BG, Nielsen SF, Flyger H, Milne RL, Arias Perez JI, Menendez P, Muller H, Arndt V, Stegmaier C, Lichtner P, Lochmann M, Justenhoven C, Ko YD, The GenicaNetwork, Muranen TA, Aittomaki K, Blomqvist C, Greco D, Heikkinen T, Ito H, Iwata H, Yatabe Y, Antonenkova NN, Margolin S, Kataja V, Kosma VM, Hartikainen JM, Balleine R, kConFab Investigators, Tseng CC, Van Den Berg D, Stram DO, Neven P, Dieudonne AS, Leunen K, Rudolph A, Nickels S, Flesch-Janys D, Peterlongo P, Peissel B, Bernard L, Olson JE, Wang X, Stevens K, Severi G, Baglietto L, McLean C, Coetzee GA, Feng Y, Henderson BE, Schumacher F, Bogdanova NV, Labreche F, Dumont M, Yip CH, Mohd Taib NA, Cheng CY, Shrubsole M, Long J, Pylkas K, Jukkola-Vuorinen A, Kauppila S, Knight JA, Glendon G, Mulligan AM, Tollennar RAEM, Seynaeve CM, Kriege M, Hooning MJ, van den Ouweland AMW, van Deurzen CHM, Lu W, Gao YT, Cai H, Balasubramnian SP, Cross SS, Reed MWR, Signorello L, Cai Q, Shah M, Miao H, Chan CW, Chia KS, Jakubowska A, Jaworska K, Durda K, Hsiung CN, Wu PE, Yu JC, Ashworth A, Jones M, Tessier DC, Gonzalez-Neira A, Pita G, Alonso MR, Vincent D, Bacot F, Ambrosone CB, Bandera EV, John EM, Chen GK, Hu JJ, Rodiquz-Gil JL, Bernstein L, Press MF, Ziegler RG, Millikan RM, Deming-Halverson SL, Nyante S, Ingles SA, Waisfisz Q, Tsimikilis H, Makalic E, Schmidt D, Bui M, Gibson L, Muller-Myhsok B, Hein R, Dahmen N, Beckmann L, Aaltonen K, Czene K, Irwanto A, Liu J, Turnbull C, FBCS, Rahman N, Meijers-Heijboer H, Uitterlinden AG, Rivadeneira F, ABCTB Investigators Olswold C, Slager S, Pilarski R, Ademuyiwa F, Konstantopoulou I, Martin NG, Montgomery GW, Slamon DJ, Rauh C, Lux MP, Jud SM, Bruning T, Weaver JE, Sharma P, Pathak H, Tapper W, Gerty S, Durcan L, Trichopoulos D, Tumino R, Peeters PH, Kaaks R, Campa D, Canzian F, Weiderpass E, Johansson M, Khaw KT, Travis R, Clavel-Chapelon F, Kolonel LN, Chen C, Beck A, Hankinson SE, Berg C, Hoover RN, Lissowska J, Figueroa J, Chasman DI, Gaudet MM, Diver WR, Willett WC, Hunter DJ, Simard J, Benitez J, Duning AM, Sherman ME, Chenevix-Trench G, Chanock SJ, Hall P, Pharoah P, Vachon C, Easton DF, Haiman CA, Kraft P. Genome-wide association studies identify four ER-negative specific breast cancer risk loci .Nat Genet. 2013;45(4):392-8.
  49. Tamura T, Morita E, Kawai S, Okada R, Naito M, Wakai K, Hori Y, Kondo T, Hamajima N. Significant association of urokinase plasminogen activator Pro141Leu with serum lipid profiles in a Japanese population .Gene. (Published online, Apr 26, 2013).
  50. Higashibata T, Naito M, Mori A, Ozawa N, Furuta M, Tsuchiya R, Koyama E, Morita E, Kawai S, Okada R, Yin G, Wakai K, Hamajima N. DPP4 genetic variants influence baseline prostate-specific antigen levels: the J-MICC Study .Nagoya J Med Sci. 2013;75:73-80.
  51. Takami H, Nakamoto M, Uemura H, Katsuura S, Yamaguchi M, Hiyoshi M, Sawachika F, Juta T, Arisawa K. Inverse Correlation Between Coffee Consumption and Prevalence of Metabolic Syndrome: Baseline Survey of the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study in Tokushima, Japan .J Empidemiol. 2013;23:12-20.
  52. Morita E, Aoyama K, Tamura T, Okada R, Kawai S, Ito Y, Naito M, Wakai K, Hamajima N. Large-scale survay of frequency of forest walking and realted factors in a Japanese population inhabiting a large city and comparison of an urban area and a rural area .J Forest Res. (Published online, Nov 27, 2012).
  53. Okada Y, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Kawaguchi T, Stahl EA, Kurreeman FA, Nishida N, Ohmiya H, Myouzen K, Takahashi M, Sawada T, Nishioka Y, Yukioka M, Matsubara T, Wakitani S, Teshima R, Tohma S, Takasugi K, Shimada K, Murasawa A, Honjo S, Matsuo K, Tanaka H, Tajima K, Suzuki T, Iwamoto T, Kawamura Y, Tanii H, Okazaki Y, Sasaki T, Gregersen PK, Padyukov L, Worthington J, Siminovitch KA, Lathrop M, Taniguchi A, Takahashi A, Tokunaga K, Kubo M, Nakamura Y, Kamatani N, Mimori T, Plenge RM, Yamanaka H, Momohara S, Yamada R, Matsuda F, Yamamoto K. Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population .Nat Genet. 2012;25;44(5):511-6.
  54. Yuasa Y, Nagasaki H, Oze I, Akiyama Y, Yoshida S, Shitara K, Ito S, Hosono S, Watanabe M, Ito H, Tanaka H, Kang D, Pan KF, You WC, Matsuo K. Insulin-like growth factor 2 hypomethylation of blood leukocyte DNA is associated with gastric cancer risk .Int J Cancer. 2012;131(11):2596-603.
  55. Lan Q, Hsiung CA, Matsuo K, Hong YC, Seow A, Wang Z, Hosgood HD 3rd, Chen K, Wang JC, Chatterjee N, Hu W, Wong MP, Zheng W, Caporaso N, Park JY, Chen CJ, Kim YH, Kim YT, Landi MT, Shen H, Lawrence C, Burdett L, Yeager M, Yuenger J, Jacobs KB, Chang IS, Mitsudomi T, Kim HN, Chang GC, Bassig BA, Tucker M, Wei F, Yin Z, Wu C, An SJ, Qian B, Lee VH, Lu D, Liu J, Jeon HS, Hsiao CF, Sung JS, Kim JH, Gao YT, Tsai YH, Jung YJ, Guo H, Hu Z, Hutchinson A, Wang WC, Klein R, Chung CC, Oh IJ, Chen KY, Berndt SI, He X, Wu W, Chang J, Zhang XC, Huang MS, Zheng H, Wang J, Zhao X, Li Y, Choi JE, Su WC, Park KH, Sung SW, Shu XO, Chen YM, Liu L, Kang CH, Hu L, Chen CH, Pao W, Kim YC, Yang TY, Xu J, Guan P, Tan W, Su J, Wang CL, Li H, Sihoe AD, Zhao Z, Chen Y, Choi YY, Hung JY, Kim JS, Yoon HI, Cai Q, Lin CC, Park IK, Xu P, Dong J, Kim C, He Q, Perng RP, Kohno T, Kweon SS, Chen CY, Vermeulen R, Wu J, Lim WY, Chen KC, Chow WH, Ji BT, Chan JK, Chu M, Li YJ, Yokota J, Li J, Chen H, Xiang YB, Yu CJ, Kunitoh H, Wu G, Jin L, Lo YL, Shiraishi K, Chen YH, Lin HC, Wu T, Wu YL, Yang PC, Zhou B, Shin MH, Fraumeni JF Jr, Lin D, Chanock SJ, Rothman N. Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia .Nat Genet. 2012;11;44(12):1330-5.
  56. Kawaguchi T, Sumida Y, Umemura A, Matsuo K, Takahashi M, Takamura T, Yasui K, Saibara T, Hashimoto E, Kawanaka M, Watanabe S, Kawata S, Imai Y, Kokubo M, Shima T, Park H, Tanaka H, Tajima K, Yamada R, Matsuda F, Okanoue T. Genetic Polymorphisms of the Human PNPLA3 Gene Are Strongly Associated with Severity of Non-Alcoholic Fatty Liver Disease in Japanese .Plos One. 2012;7(6):e38322.
  57. Yanagisawa K, Tomida S, Matsuo K, Arima C, Kusumegi M, Yokoyama Y, Ko SB, Mizuno N, Kawahara T, Kuroyanagi Y, Takeuchi T, Goto H, Yamao K, Nagino M, Tajima K, Takahashi T. Seven-signal proteomic signature for detection of operable pancreatic ductal adenocarcinoma and their discrimination from autoimmune pancreatitis .Int J Proteomics. 2012;2012:510397.
  58. Okada R, Wakai K, Naito M, Morita E, Kawai S, Yin G, Ozawa N, Furuta M, Koyama E, Tsuchiya R, Kouno N, Hamajima N. Renal Hyperfiltration in Prediabetes Confirmed by Fasting Plasma Glucose and Hemoglobin A1c .Ren Fail. 2012;34:1084-90.
  59. Naito M, Asai Y, Mori A, Fukada Y, Kuwabara M, Katase S, Hishida A, Morita E, Kawai S, Okada R, Nishio K, Tamakoshi A, Wakai K, Hamajima N. Association of obesity and diabetes with serum prostate-specific antigen levels in Japanese males .Nagoya J Med Sci. 2012;74:285-292.
  60. Hamajima N, Naito M, Okada R, Kawai S, Yin G, Morita E, Higashibata T, Tamura T, Nakagawa H, Matsuo H, Mori A, Wakai K. Significant interaction between LRP2 rs2544390 in intron 1 and alcohol drinking for serum uric acid levels among a Japanese population .Gene. 2012;503:131-6.
  61. Tamura T, Morita E, Kondo T, Ueyama J, Tanaka T, Kida Y, Hori Y, Inoue S, Tomita K, Okada R, Kawai S, Hishida A, Naito M, Wakai K, Hamajima N. Prevalence of Helicobacter pylori infection measured with urinary antibody in an urban area of Japan, 2008-2010 .Nagoya J Med Sci. 2012;74:63-70.
  62. Hirasada K, Niimura H, Kubozono T, Nakamura A, Tatebo M, Ogawa S, Tsunematsu N, Chiba S, Matsushita T, Kusano K, Miyata M, Takezaki T. Values of cardio-ankle vascular index (CAVI) between Amami islands and Kagoshima mainland among health checkup examinees .J Atheroscler Thromb. 2012;19:69-80.

    →「あまみ島嶼地域における動脈硬化」

  63. Nobata S, Hishida A, Naito M, Asai Y, Mori A, Kuwabara M, Katase S, Okada R, Morita E, Kawai S, Hamajima N, Wakai K. Association between KLK3 rs2735839 G/A polymorphism and serum PSA levels in Japanese men .Urol Int. (in press).
  64. Islam T, Ito H, Sueta A, Hosono S, Hirose K, Watanabe M, Iwata H, Tajima K, Tanaka H, Matsuo K. Alcohol and dietary folate intake and risk of breast cancer: a case-control study in Japan .Eur J Cancer. 2012;22(4):358-66.
  65. Islam T, Matsuo K, Ito H, Hosono S, Watanabe M, Iwata H, Tajima K, Tanaka H. Reproductive and hormonal risk factors for luminal, HER2-overexpressing, and triple-negative breast cancer in Japanese women .Ann Oncol. 2012;23(9):2435-41.
  66. Kawakita D, Sato F, Hosono S, Ito H, Oze I, Watanabe M, Hanai N, Hatooka S, Hasegawa Y, Shinoda M, Tajima K, Murakami S, Tanaka H, Matsuo K. Inverse association between yoghurt intake and upper aerodigestive tract cancer risk in a Japanese population .Eur J Cancer Prev. 2012;21(5):453-9.
  67. Sueta A, Ito H, Kawase T, Hirose K, Hosono S, Yatabe Y, Tajima K, Tanaka H, Iwata H, Iwase H, Matsuo K. A genetic risk predictor for breast cancer using a combination of low-penetrance polymorphisms in a Japanese population .Breast Cancer Res Treat. 2012;132(2):711-21.
  68. Shitara K, Ito S, Misawa K, Ito Y, Ito H, Hosono S, Watanabe M, Tajima K, Tanaka H, Muro K, Matsuo K. Genetic polymorphism of IGF-I predicts recurrence in patients with gastric cancer who have undergone curative gastrectomy .Ann Oncol. 2012;23(3):659-64.
  69. Chihara D, Matsuo K, Kanda J, Hosono S, Ito H, Nakamura S, Seto M, Morishima Y, Tajima K, Tanaka H. Inverse association between soy intake and non-Hodgkin lymphoma risk among women: a case-control study in Japan .Ann Oncol. 2012;23(4):1061-6.
  70. Kawakita D, Matsuo K, Sato F, Oze I, Hosono S, Ito H, Watanabe M, Yatabe Y, Hanai N, Hasegawa Y, Tajima K, Murakami S, Tanaka H. Association between dietary folate intake and clinical outcome in head and neck squamous cell carcinoma .Ann Oncol . 2012;23(1):186-92.
  71. Morita E, Hamajima N, Hishida A, Aoyama K, Okada R, Kawai S, Tomita K, Kuriki S, Tamura T, Naito M, Kondo T, Ueyama J, Kimata A, Yamamoto K, Hori Y, Hoshino J, Hamamoto R, Tsukamoto S, Onishi J, Hagikura S, Naito H, Hibi S, Ito Y, Wakai K. Profile on baseline survey of Daiko Study in the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study) .Nagoya J Med Sci. 2011;73:185-193.
  72. Cai Q, Long J, Lu W, Qu S, Wen W, Kang D, Lee JY, Chen K, Shen H, Shen CY, Sung H, Matsuo K, Haiman CA, Khoo US, Ren Z, Iwasaki M, Gu K, Xiang YB, Choi JY, Park SK, Zhang L, Hu Z, Wu PE, Noh DY, Tajima K, Henderson BE, Chan KY, Su F, Kasuga Y, Wang W, Cheng JR, Yoo KY, Lee JY, Zheng H, Liu Y, Shieh YL, Kim SW, Lee JW, Iwata H, Le Marchand L, Chan SY, Xie X, Tsugane S, Lee MH, Wang S, Li G, Levy S, Huang B, Shi J, Delahanty R, Zheng Y, Li C, Gao YT, Shu XO, Zheng W. Genome-wide association study identifies breast cancer risk variant at 10q21.2: results from the Asia Breast Cancer Consortium .Hum Mol Genet. 2011;20(24):4991-9.
  73. Terao C, Ohmura K, Kochi Y, Ikari K, Maruya E, Katayama M, Shimada K, Murasawa A, Honjo S, Takasugi K, Matsuo K, Tajima K, Suzuki A, Yamamoto K, Momohara S, Yamanaka H, Yamada R, Saji H, Matsuda F, Mimori T. A large-scale association study identified multiple HLA-DRB1 alleles associated with ACPA-negative rheumatoid arthritis in Japanese subjects .Ann Rheum Dis. 2011;70(12):2134-9.
  74. Matsuse M, Takahashi M, Mitsutake N, Nishihara E, Hirokawa M, Kawaguchi T, Rogounovitch T, Saenko V, Bychkov A, Suzuki K, Matsuo K, Tajima K, Miyauchi A, Yamada R, Matsuda F, Yamashita S. The FOXE1 and NKX2-1 loci are associated with susceptibility to papillary thyroid carcinoma in the Japanese population .J Med Genet. 2011;48(9):645-8.
  75. Chuang SC, Agudo A, Ahrens W, Anatharaman D, Benhamou S, Boccia S Chen C, Conway D, Fabianova E, Hayes RB, Healy C, Holcatova I, Kjaerheim K, Lagiou P, Lazarus P, Macfarlane TV, Mahimkar M, Mates D, Matsuo K, Merletti F, Metspalu A, Mogenstern H, Muscat J, Cadoni G, Olshan AF, Purdue M, Ramroth H, Rudnai P, Schartz SM, Simonato L, Smith EM, Sturgis EM, Szeszenia-Dabrowska N, Talamini R, Thomson P, Wei Q, Zaidze D,Zhang ZF,Znaor A,Brennan P,Boffetta P,Hashibe M. Sequence variants and the risk of head and neck cancer: pooled analysis in the INHANCE consortium .Front Oncol. 2011;1:13.
  76. Nakata I, Yamashiro K, Yamada R, Gotoh N, Nakanishi H, Hayashi H, Tsujikawa A, Otani A, Saito M, Iida T, Oishi A, Matsuo K, Tajima K, Matsuda F, Yoshimura N. Association between the SERPING1 Gene and Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in Japanese .PLoS One. 2011;6(4):e19108.
  77. Takigawa N, Kiura K, Segawa Y, Hotta K, Tamaoki A, Touda Y, Nagata T, Watanabe K, Gemba K, Moritaka T, Horita N, Takeda H, Okimoto N, Takemoto M, Matsuo K, Shinkai T, Tabata M, Ueoka H, Knazawa S, Tanimoto M. Benefits and adverse events among elderly patients receiving concurrent chemoradiotherapy for locally advanced non-small cell lung cancer: Analysis of the Okayama Lung Cancer Study Group Trial 0007 .J Thorac Oncol . 2011;6(6):1087-91.
  78. Saeki N, Saito A, Choi IJ, Matsuo K, Ohnami S, Totsuka H, Chiku S, Kuchiba A, Lee YS, Yoon KA, Kook MC, Park SR, Kim YW, Tanaka H, Tajima K, Hirose H, Tanioka F, Matsuno Y, Sugimura H, Kato S, Nakamura T, Nishina T, Yasui W, Aoyagi K, Sasaki H, Yanagihara K, Katai H, Shimoda T, Yoshida T, Nakamura Y, Hirohashi S, Sakamoto H. A Functional Single Nucleotide Polymorphism in Mucin 1, at Chromosome 1q22, Determines Susceptibility to Diffuse-Type Gastric Cancer .Gastroenterology. 2011;140(3):892-902.
  79. Hamajima N, Naito M, Hishida A, Okada R, Asai Y, Wakai K. Serum uric acid distribution according to SLC22A12 W258X genotype in a cross-sectional study of a general Japanese population .BMC Med Genet. 2011;12:33.
  80. Hamajima N, Okada R, Kawai S, Hishida A, Morita E, Yin G, Wakai K, Matsuo H, Inoue H, Takada Y, Asai Y, Mori A, Naito M. Significant association of serum uric acid levels with SLC2A9 rs11722228 among a Japanese population .Mol Genet Metab. 2011;103:378-82.
  81. Kataoka R, Kimata A, Yamamoto K, Hirosawa N, Ueyama J, Kondo T, Okada R, Kawai S, Hishida A, Naito M, Morita E, Wakai K, Hamajima N. Association of UGT1A1 Gly71Arg with urine urobilinogen .Nagoya J Med Sci. 2011;73:33-40.
  82. Morita E, Naito M, Hishida A, Wakai K, Mori A, Asai Y, Okada R, Kawai S, Hamajima N. No association between the frequency of forest walking and blood pressure levels or the prevalence of hypertension in a cross-sectional study of a Japanese population .Environ Health Prev Med. 2011;16:299-306.

    →「森林浴と血圧の関係」

  83. Nanri H, Nakamura K, Hara M, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Tanaka K. Association between dietary pattern and serum C-reactive protein in Japanese men and women .J Epidemiol. 2011;21:122-31.

    →「食事パターンと炎症のかかわり」

  84. Nakamura K, Nanri H, Hara M, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Tanaka K. Optimal cutoff values of waist circumference and the discriminatory performance of other anthropometric indices to detect the clustering of cardiovascular risk factors for metabolic syndrome in Japanese men and women .Environ Health Prev Med. 2011;16:52-60.

    →「日本人のメタボの基準値について」

  85. Nakao M, Matsuo K, Hosono S, Ogata S, Ito H, Watanabe M, Mizuno N, Iida S, Satoh S, Yatabe Y, Yamao K, Ueda R, Tajima K, Tanaka H. ABO blood group alleles and the risk of pancreatic cancer in Japanese population .Cancer Sci 2011;102(5):1076-1080.
  86. Kanda J, Matsuo K, Suzuki T, Hosono S, Ito H, Ichinohe T, Seto M, Morishima Y, Tajima K, Tanaka H. Association between obesity and the risk of malignant lymphoma in Japanese: a case-control study .Int J Cancer. 2010;126(10):2416-25.
  87. Oze I, Matsuo K, Hosono S, Ito H, Kawase T, Watanabe M, Suzuki T, Hatooka S, Yatabe Y, Hasegawa Y, Shinoda M, Tajima K, Tanaka H. Comparison between Self-report Facial Flushing After Alcohol Consumption and ALDH2 Glu504Lys Polymorphism for the Risk of Upper Aerodigestive Tract Cancer in a Japanese Population .Cancer Sci. 2010;101(8):1875-80.
  88. Park JY, Matsuo K, Suzuki T, Ito H, Hosono S, Kawase T, Watanabe M, Oze I, Hida T, Yatabe Y, Mitsudomi T, Takezaki T, Tajima K, Tanaka H. Impact of smoking on lung cancer risk is stronger in those with the homozygous aldehyde dehydrogenase 2 null allele in a Japanese population .Carcinogenesis. 2010;31(4):660-665.
  89. Kawase T, Matsuo K, Suzuki T, Hirose K, Hosono S, Watanabe M, Inagaki M, Iwata H, Tanaka H, Tajima K. Association between vitamin D and calcium intake and breast cancer risk according to menopausal status and receptor status in Japan .Kawase T, Matsuo K, Suzuki T, Hirose K, Hosono S, Watanabe M, Inagaki M, Iwata H, Tanaka H, Tajima K.
  90. Hosono S, Matsuo K, Kajiyama H, Hirose K, Suzuki T, Kawase T, Kidokoro K, Nakanishi T, Hamajima N, Kikkawa F, Tajima K, Tanaka H. Association between dietary calcium and vitamin D intake and cervical carcinogenesis among Japanese women .Eur J Clin Nutr. 2010;64(4):400-409.
  91. Kanda J, Matsuo K, Inoue M, Iwasak M, Sawada N, Shimazu T, Yamaji T, Sasazuki S, Tsugane S. Association of alcohol intake with the risk of malignant lymphoma and plasma-cell myeloma in Japanese: A population-based cohort study (JPHC study) .Cancer Epidemiol Biomarker Prev. 2010;19(2):429-34.
  92. Ito H, Matsuo K, Hosono S, Watanabe M, Kawase T, Suzuki T, Hirai T, Yatabe Y, Tanaka H, Tajima K. Association between CYP7A1 loci and the risk of proximal colorectal cancer in Japanese .Int J Mol Epi Genet. 2010;1: 35-46.
  93. 森田えみ, 内藤真理子, 西尾和子, 石田喜子, 菱田朝陽, 若井建志, 浅井八多美, 浜島信之. 人間ドック受診者を対象とした静岡県中西部地区における森林散策頻度に関する大規模調査 .日本森林学会誌. 2010;92:110-114.

    →「静岡地区参加者の森林散策回数」

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